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You can work in the US while waiting for your green card if you already have a valid work visa. If not, you must apply for a work permit by filing form I-765.
If you do not already have a valid work visa, you are not allowed to start working in the US until you obtain a work permit by filing form I-765.
If you already have a valid work visa, such as an H-1B or L-1 visa, you can usually work in the US even while applying for a green card.